Centrophenoxine against aging and in protecting neurons.

It is an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA).

Centrophenoxin (Meclofenoxate) was developed in 1959, and its applications included the treatment of Alzheimer’s.

Indications for use

• Chronic emotional disorders;
• neuroses accompanying depression;
• some forms of schizophrenia;
• psychoorganic syndromes caused by atherosclerosis;
• chronic fatigue and difficulty concentrating in children;
• bedwetting in adults and children.

Centrophenoxine is an extremely safe and effective nootropic substance. In one study, doses of 3 grams per day were administered to patients for a year. The average age of the patients was 59. The bone marrow remained unchanged. A number of indicators related to kidney and liver function showed no negative changes after this long-term treatment with an extremely high daily dose.

The main benefits of taking centrophenoxine

• Increases acetylcholine levels in certain areas of the brain, which affects cognitive function and memory;
• removes lipofuscin from the brain. This is one of the products of cell metabolism. As we age, more and more of it is deposited in cells. This is the same substance that is responsible for the pale gray spots on the skin of aging people;
• improves blood flow in the brain and increases the amount of oxygen delivered to neurons;
• Centrophenoxine is also known as meclofenoxate or Lucidril (generic name). It is a molecule formed by combining DMAE with parachlorophenoxyacetic acid (pCPA).

So what is the difference in effect between DMAE and centrophenoxine?

First of all, centrophenoxine easily crosses the blood-brain barrier. This allows it to work directly in the brain. As for DMAE, there are doubts as to whether this substance itself reaches the brain at all and, if so, to what extent. Certainly centrophenoxine is much more efficient.

Essentially, centrophenoxine largely duplicates the actions of DMAE. However, it works better and more efficiently. Here’s what both DMAE and centrophenoxine do in the body:

• Increase the concentration of acetylcholine in the body, including in the brain;
• reduce oxidative stress on several levels;
• improve plasticity of cell membranes;
• protect neurons from toxins.

How does this action translate into practical results that will appeal to the non-specialist?

• Improves memory;
• increases concentration;
• accelerates the learning process;
• rejuvenates internal organs and skin;
• prolongs life;
• reduces symptoms of ADHD (excessive agitation and jitteriness).

If centrophenoxine is used in the morning, it will give a certain, albeit small, amount of energy. This will have to do with invigorating the mind. Energy for the body must be provided in other ways. The mind will be invigorated as a result of better blood circulation to the brain and supplying it with more fuel – oxygen.

What to combine centrophenoxine with?

Generally available scientific studies on the subject do not exist. On the other hand, one can rely on the opinions of people who experiment on themselves with various substances. According to them, centrophenoxine combines well and works in synergy with racetams such as Noopept, Piracetam or Aniracetam. It can be suspected that it will also synergize well with other racetams.

Contraindications

• Epilepsy;
• states of agitation.