Ergoloid mesylates
€18.50 – €34.50
Ergoloid mesylates (Hydergine) powder
SKU: ergoloid
ACTIVE INGREDIENT: Dihydroergotoxine Mesylate
OTHER NAMES: Dihydroergotoxine mesilate; Coristin; DIHYDRO-ERGOTOXIN METHANESULFONATE; DIHYDROERGOTOXINE METHANE SULFONATE; DIHYDROERGOTOXINE MESYLATE (Ergoloid mesylate,Co-dergocrine mes.); Ergoloid Mesylate; Ergotoxine,dihydro-,monomethanesulfonate (salt); Inorter (TN); Ergotoxine, dihydro-, monomethanesulfonate (salt) (9CI); An equiproportional mixture of dihydroergocornine mesylate, dihydroergocristine mesylate, and ratio of dihydro-alpha-ergocryptine mesylate to dihydro-beta-ergocryptine mesylate is 1.5-2.5:1; Trigot; Dihydroergotoxine monomethanesulfonate (salt); Hydergin; Ergotaman-3,6,18-trione, 9,10-dihydro-12-hydroxy-2,5-bis(1-methylethyl)-, (5alpha,10alpha)-, monomethanesulfonate (salt) mixture with 9,10alpha-dihydro-12-hydroxy-2-(1-methylethyl)-5alpha-(phenylmethyl)ergotaman-3,6,18-trione monomethanesulfonate (salt), 9,10alpha-dihydro-12-hydroxy-2-(1-methylethyl)-5alpha-(2-methylpropyl)ergotaman-3,6,18-trione monomethanesulfonate (salt), and 9,10alpha-dihydro-12-hydroxy-2-(1-methylethyl)-5alpha-(1-methylpropyl)ergotaman-3,6,18-trione monomethanesulfonate (salt); Circanol (TN); Ergotoxine, dihydro-, methanesulfonate; Dihydroergotoxin methanesulfonate;42615-51-0; Inorter;Prestwick_746;12645-43-1; Ergoloid mesylates (USP);Redergin;52655-92-2; Dihydroergotoxin mesylate;CCK 179; Ergoloid Mesylates [USAN]; Circanol; Ergoloid mesylates; 8031-73-0; Dihydroergotoxine mesilate (JP14); 11006-63-6; Ischelium; Dihydroergotoxine methanesulphonate; Dihydroergotoxine methanesulfonate; Hydergine; CO-Dergocrine mesylate
CAS NUMBER: 8067-24-1
ATC CODE: C04AE01
FORMULA: C19H25N3O2 . CH4O3S
MOLAR MASS: 8067-24-1.mol
ITEM TYPE: powder
QUANTITY PER PACK: 1 gram and 2 grams
STORAGE: Store in a cool and dry place. Keep away from direct sunlight and heat. Keep out of reach of children.
SCOOPS: This product includes a measuring scoop (red) = 6 mg (approximately).
The product is not intended for human use. For laboratory use only.
Ergoloid mesylate is a nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
Ergoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the fungus Claviceps purpurea and are all derivatives of the tetracyclic compound 6-methylergonovine. The derivatives of this fungus are identified to be about 350 different substances from which the components of the ergoloid mesylate mixture are composed of the dihydrogenated ergot alkaloid derivatives. The mixture of ergoloid mesylate was first developed by Novartis and FDA approved on November 5, 1953, but this specific formulation is now discontinued. Later in 1991, the mixture of ergoloid mesylates was retaken by Sun Pharmaceutical Industries and approved by the FDA.
Source: https://go.drugbank.com/drugs/DB01049
It was developed by Albert Hofmann (the discoverer of LSD) for Sandoz (now part of Novartis).
Hydergine, is a mixture of the methanesulfonate salts of three dihydrogenated ergot alkaloids (dihydroergocristine, dihydroergocornine, and alpha- and beta-dihydroergocryptine).
A systematic review published in 1994 found little evidence to support the use of ergoloid mesylates, concluding only that potentially effective doses may be higher than those currently approved in dementia treatment.
Ergoloid Mesylate Tablets USP for sublingual use contain 1 mg of Ergoloid Mesylates USP, a mixture of the methanesulfonate salt of the following hydrogenated alkaloids: Dihydroergocornine mesylate 0.333 mg, Dihydroergocristine mesylate 0.333 mg, Dihydroergocryptine mesylate 0.333 mg.
It has been used to treat hyperprolactinemia (high prolactin levels).