Flmodafinil powder >99,5%

Flmodafinil, also known as lauflumide or bisfluoromodafinil, originally developed under the name of CRL-40,940 and currently researched as NLS-4 (not to be confused with fladrafinil, first known as CRL-40,941 and sometimes referred to as fluorafinil) is the bisfluoro analog of modafinil – an eugeroic (wakefulness-promoting) and atypical stimulant that happens to be the first ever nootropic agent with scientifically proven cognitive benefits in healthy individuals.

It is believed to have higher bioavailability than modafinil due to the addition of two fluorine atoms to the molecule, and up to four times more potent for the same reason.

In 2015 mice studies, flmodafinil increased the drug-induced wakefulness duration to a significant extent relative to modafinil – the effect achieved with less than half of the dose used for latter. No hyperactivity or rebound hypersomnia was observed. Despite the fact that the mice stayed awake longer, the delta waves increase period during NREM sleep was shorter in the animals treated with flmodafinil, which indicates faster recovery.

NLS Pharmaceutics Ltd. report that flmodafinil did not induce any of CYP450 enzymes (including CYP3A4) in in vitro human studies, whereas clinically significant induction of CYP450 enzymes often happens with repeated dosing of modafinil.

It has also recently been demonstrated that flmodafinil may exert inhibitory activity on ACE2 and Cathepsin L, and as such should be investigated for COVID-19 treatment.

Anecdotal evidence suggests that the compound is capable of producing an extremely clear-headed state of mind (even unparalleled), sometimes as soon as 15 minutes after dosing, and consistently quicker acting than modafinil. While subjective effects of flmodafinil are generally more pronounced, its users tend to experience significantly less physical effects. In fact, despite its stimulant properties, some report that the compound does not interfere with their ability to fall asleep.

Benefits of taking flmodafinil 

• clarity of mind;
• increased alertness and wakefulness;
• reduced fatigue in times of sleep deprivation;
• highly improved focus and concentration;
• enhanced mood;
• inner calm and contentment (no inner tension);
• greatly decreased impulsivity;
• boost in productivity;
• no residual insomnia;
• high dosing schedule flexibility;
• lower risk of drug interactions.

Side effects of flmodafinil

As mentioned before, flmodafinil comes with less side effects than modafinil, and the below are more likely to be experienced with high doses.

• headache;
• dizziness;
• nausea;
• diarrhea;
• appetite loss;
• insomnia.

Dosage

The actual potency of flmodafinil seems to be about twice that of modafinil.
In many users, a single dose lasts for ca. 6 hours, however, based on anecdotal evidence, it seems to vary, so one needs to determine the actual duration for oneself.

Flmodafinil is best to be taken on empty stomach, with effective and recommended doses ranging from 25 to 100 mg. In order to avoid side effects, it is advised not to exceed 200 mg per day.