€14.80
Picamilon powder
SKU: picamilon
ACTIVE INGREDIENT: Picamilon
ADDITIONAL INGREDIENTS: –
OTHER NAMES: GABA-NG; nicotinoyl-GABA; Picamilon; Pikamilon; Picamilone
CAS NUMBER: 34562-97-5
ATC CODE: N02CX
FORMULA: C10H12N2O3
MOLAR MASS: 208.217 g·mol−1
ITEM TYPE: powder
QUANTITY PER PACK: 5 grams
STORAGE: Store in a cool and dry place. Keep away from direct sunlight and heat. Keep out of reach of children.
A micro spoon is added to Picamilon (blue) = 40 mg (approximately).
The product is not intended for human use. For laboratory use only.
Developed in Russia in 1969, picamilon has been used as a medication to treat has been used since 1986 as a pharmaceutical in Russia to treat attention, memory, and learning issues as well as brain blood circulation loss, traumatic brain injury, neurological deficits in chronic alcoholism and other disorders. While it is currently somewhat recognized by the nootropic community, it is largely underrated due to how subtle its effects feel in comparison with another Russian invention – phenibut.
The idea behind picamilon design is brilliant in its simplicity – in order to make the blood-brain barrier more permeable towards the inhibitory neurotransmitter gamma aminobutyric acid (GABA), its particle is linked to that of niacin (also known as vitamin B3 or nicotinic acid). The link between the two is assumed to break down upon its entrance into the brain. That said, taking GABA and niacin as a stack will not produce the same effect.
GABA activates GABA receptors producing an anxiolytic response, while niacin acts as a vasodilator relaxing constricted blood vessels and increasing cerebral blood flow and thus enhancing GABA activity. Furthermore, niacin itself is vital for the synthesis of serotonin, which also accounts for the anxiolytic action of picamilon.
It is currently apparent that low GABA levels lead to anxiety, depression and insomnia and restoring the GABA – glutamate balance relieves the overstimulated neurons and promotes a positive mood. As a GABA-ergic subatance, picamilon is unique in that in enhances cerebral blood flood, and more efficiently so than piracetam or vinpocetine. Also, the niacin component enhances cell metabolism and oxygen supply in the brain, resulting in an improvement in short-term and long-term memory.
Picamilon has been shown to normalize serotonin and dopamine content, and dopamine uptake in the brain, which further explains its effect on memory formation, attention, focus, and cognition.
It has been valued by those who seek relief from anxiety which is not accompanied by a feeling of inebriation or sedation.
Benefits of taking picamilon
Side-effects
Dosage
Picamilon is usually taken orally two or three times a day. A typical single anxiolytic dose is 50 mg, however, when one wishes to experience more of its cognitive enhancing, mildly stimulating side, 100 mg would serve this purpose better.