€25.00
Safinamide mesylate
SKU: safinamide
ACTIVE INGREDIENT: safinamide mesylate
ADDITIONAL INGREDIENTS: –
OTHER NAMES: (S)-2-((4-(3-fluorobenzoxy)benzyl)amino)propanamide;2-(4-(3-fluorobenzyloxy)benzylamino)propionamide; fbap methanesulfonate; FCE 26743; FCE 28073; FCE-26743; FCE-28073; NW-1015; PNU 151774E; PNU-151774E; safinamide; safinamide methanesulfonate; Xadago
CAS NUMBER: 202825-46-5
ATC CODE: N04BD03
FORMULA: C18H23FN2O5S
MOLAR MASS: 398.449 g/mol
ITEM TYPE: Powder
QUANTITY PER PACK: 1 gram
SERVINGS PER PACK: –
SUGGESTED USE: –
STORAGE: Store in a cool and dry place. Keep away from direct sunlight and heat.
WARNING: Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drugs or over the counter medications.
DISCLAIMER: Always consult with a qualified health physician before taking any new dietary supplement. This product is not intended to diagnose, treat, cure, or prevent any diseases.
SCOOPS: This product includes a measuring scoop (blue) = 40 mg (approximately).
The product is not intended for human use. For laboratory use only.
Safinamide mesylate is the methanesulfonic acid form of its active component safinamide, a selective and reversible monoamine oxidase B (MAO-B) inhibitor with the value of 50% inhibition concentration IC50 of 98 nM. Having been used for the treatment of Parkinson’s disease (PD), safinamide potently modulates dopamine (DA), a substrate of MAO-B, suppressing DA uptake and reversibly binds to MAO-B blocking the function of MAO-B, which lead to the relief of PD symptoms. Besides MAO-B inhibition, safinamide exhibits novel anticonvulsant activities, including sodium channel blockade, calcium channel blockade and glutamate release inhibition, with values of IC50 of 8.2 μM, 31.5 μM and >56.4 μM respectively.