• Selegiline hydrochloride - Zion Pharma
  • Selegiline hydrochloride molecule - Zion Pharma
  • Selegiline HCl - Zion Pharma

Selegiline hydrochloride (IMAO) powder – pharmaceutical grade

23.00169.00

Selegiline is a medication which is used in the treatment of Parkinson’s disease and major depressive disorder.

Selegiline acts as a monoamine oxidase inhibitor (IMAO), and increases levels of monoamine neurotransmitters in the brain.

At typical doses used in Parkinson’s disease, selegiline is a selective and irreversible inhibitor of monoamine oxidase B (MAO-B), increasing dopamine levels in the brain. At higher doses (above 20 mg/day), it loses its selectivity for MAO-B and also inhibits MAO-A, which increases serotonin and norepinephrine levels in the brain.

SKU: selegiline-hydrochloride-powder

ACTIVE INGREDIENT: Selegiline hydrochloride >99%

OTHER NAMES: L-deprenyl, Eldepryl, Emsam, Jumex, Zelapar, (R)-(–)-N,α-Dimethyl-N-2-propynylphenethylamine; (R)-(–)-N-Methyl-N-2-propynylamphetamine; (R)-(–)-N-2-propynylmethamphetamine

CAS NUMBER: 14611-52-0

ATC CODE: N04BD01, QN06AX90

FORMULA: C13H17N•ClH

ITEM TYPE: Powder

QUANTITY PER PACK: 0.5 to 5 g

SERVINGS PER PACK:

SUGGESTED USE:

STORAGE: Store in a cool and dry place. Keep away from direct sunlight and heat.

WARNING: Keep out of reach of children. Do not take any supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drugs or over the counter medications.

DISCLAIMER: Always consult with a qualified health physician before taking any new dietary supplement.
The product is not intended for human use.
For laboratory use only.

SCOOPS: This product includes a measuring scoop (red) = 3 mg (approximately).

Read details about this substance:
https://www.drugs.com/monograph/selegiline.html

Selegiline is a long-known MAO inhibitor that is used to treat patients with Parkinson’s disease, Alzheimer’s disease and depression. In addition, the drug is used for ADHD, bipolar disorder, mood disorders and to protect nerve cells.

Selegiline – for Parkinson’s and Alzheimer’s disease

It works well in situations that require alertness and attention.

It also has antioxidant and neuroregenerative properties that can help it protect the brain, especially in older people.
It is sometimes claimed that it can also help with anxiety.

Selegiline increases levels of dopamine, serotonin and possibly other monoamines by preventing their breakdown.

Selegiline is a well-known medication an effective treatment for depression. MAO inhibitors have been displaced in favor of SSRIs, which are not accepted by many patients because of the damage they do to the body. They cause, among other things, passivity in behavior, unwillingness to change things, and impotence. These drawbacks are absent from drugs such as selegiline.

Below is information about selegiline from the drugs.com website. Only a part of the information is here. For the rest of the information, please refer to the provided link.

Related treatment

  • ADHD;
  • depression;
  • major depressive disorder.

Uses for Selegiline

Parkinsonian Syndrome

Used as adjunctive therapy for symptomatic treatment of parkinsonian syndrome (e.g., parkinsonism, Parkinson disease [paralysis agitans]) in patients who exhibit a deteriorating response to levodopa/carbidopa; designated an orphan drug by FDA for this condition. Appears to be most beneficial when used during the early stages of the “wearing off” effect. Especially useful in improving “end-of-dose” motor fluctuations.

Has been used as monotherapy in patients with newly diagnosed parkinsonian syndrome [off-label]. Because selegiline is well tolerated and possibly neuroprotective (i.e., reduces the rate of progression of parkinsonian syndrome ), some clinicians initiate therapy with selegiline in such patients, reserving levodopa or another agent (i.e., dopamine agonist) until manifestations become severe enough to warrant more aggressive therapy. However, the manufacturers state that there is no evidence from controlled studies indicating that selegiline provides benefit in the absence of concurrent levodopa therapy.

Alzheimer’s Disease

Has been used with equivocal results for the palliative treatment of mild to moderate dementia of the Alzheimer’s type [off-label] (Alzheimer’s disease, presenile or senile dementia).

Selegiline Dosage and Administration

Administration

Administer orally.

Oral Administration

Administer orally as conventional tablets, capsules, or orally disintegrating tablets.

Administer conventional tablets and capsules in 2 equally divided doses daily with breakfast and lunch.

Administer orally disintegrating tablets (Zelapar) once daily in the morning before breakfast. Avoid foods or liquids for 5 minutes prior to and after administration. Do not remove tablets from blister pack until just prior to administration. With dry hands, peel backing off 1 or 2 blister packs (depending on dosage); gently remove tablet(s) and place on tongue where dissolution occurs in seconds. (See Absorption under Pharmacokinetics.) (…)

All data on this site is for information purposes only.