• Tropoflavin - Zion Pharma

Tropoflavin (7,8-dihydroxyflavone) – powder

16.5031.50

Tropoflavin (7,8-dihydroxyflavone) – powder >98%

SKU: tropoflavin-powder

ACTIVE INGREDIENT: Tropoflavin (7,8-dihydroxyflavone) >98%

ADDITIONAL INGREDIENTS:

OTHER NAMES: Flavone,7,8-dihydroxy- (6CI); 7,8-dihydroxy-2-phenyl-4H-chromen-4-one; 7,8-dihydroxyflavone;

CAS NUMBER: 38183-03-8

ATC CODE:

FORMULA: C15H10O4

MOLAR MASS: 254.241 g·mol−1

ITEM TYPE: Powder

QUANTITY PER PACK:  1 to 2 grams

SERVINGS PER PACK:

SUGGESTED USE:

STORAGE: Store in a cool and dry place. Keep away from direct sunlight and heat.

WARNING: Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drugs or over the counter medications.

DISCLAIMER: Always consult with a qualified health physician before taking any new dietary supplement. This product is not intended to diagnose, treat, cure, or prevent any diseases.

SCOOPS: This product includes a measuring scoop (yellow) = 16 mg (approximately – big.).

The product is not intended for human use. For laboratory use only.

Tropoflavin, also known as 7,8-dihydroxyflavone, is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It acts as a potent and selective small-molecule agonist of the tropomyosin receptor kinase B (TrkB), the main signaling receptor of BDNF (brain-derived neurotrophic factor).

In animal studies, tropoflavin has demonstrated therapeutic efficacy in a wide range of central nervous system disorders, including Alzheimer’s, Parkinson’s, Huntington’s, depression, cognitive deficits in schizophrenia, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile X syndrome, and Rett syndrome. Furthermore, studies on rodents suggest that tropoflavin might ameliorate age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy subjects. Moreover, tropoflavin possesses powerful antioxidant activity independent of its actions on the TrkB receptor, protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity. Tropoflavin was also found to block methamphetamine-induced dopaminergic neurotoxicity.

Benefits of taking tropoflavin

  • improved memory;
  • enhanced, stable mood;
  • boost in energy;
  • neuroprotection and neuroplasticity;
  • antioxidant effects;
  • balanced microbiome;
  • possible aid in losing weight;
  • possible aid in drug use cessation.

Side effects

Based on existing evidence, there appears to be a low risk of adverse effects from tropoflavin.

  • restlessness;
  • overstimulation;
  • increased heart rate;
  • gastrointestinal issues;
  • dizziness;
  • irritability;
  • nausea;
  • insomnia.

Counterindications

  • epilepsy.

Dosage

Typical dosage of tropoflavine is 10 – 30 mg per day taken orally in a single dose, preferably in the morning in order to avoid trouble sleeping.