Tropoflavin (7,8-dihydroxyflavone)
Price range: €16.50 through €31.50
Tropoflavin (7,8-dihydroxyflavone)
SKU: tropoflavin
ACTIVE INGREDIENT: Tropoflavin
OTHER NAMES: Flavone,7,8-dihydroxy- (6CI); 7,8-dihydroxy-2-phenyl-4H-chromen-4-one; 7,8-dihydroxyflavone;
CAS NUMBER: 38183-03-8
ATC CODE: –
FORMULA: C15H10O4
MOLAR MASS: 254.241 g·mol−1
ITEM TYPE: powder
QUANTITY PER PACK: 1 gram and 2 grams
STORAGE: Store at room temperature. Keep away from direct sunlight and heat. Keep out of reach of children.
SCOOPS: This product includes a measuring scoop (0.025 ml) = 16 mg (approximately).
For precise measurement, we recommend using a laboratory scale.
The product is not intended for human use. For collectors, hobbyists, education and research.
All information provided here is for informational purposes only and may contain inaccuracies. These products are intended for collectors, hobbyists, and for educational and research purposes only. Not for use by humans or animals.
Tropoflavin, also known as 7,8-dihydroxyflavone, is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It acts as a potent and selective small-molecule agonist of the tropomyosin receptor kinase B (TrkB), the main signaling receptor of BDNF (brain-derived neurotrophic factor).
In animal studies, tropoflavin has demonstrated therapeutic efficacy in a wide range of central nervous system disorders, including Alzheimer’s, Parkinson’s, Huntington’s, depression, cognitive deficits in schizophrenia, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile X syndrome, and Rett syndrome. Furthermore, studies on rodents suggest that tropoflavin might ameliorate age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy subjects. Moreover, tropoflavin possesses powerful antioxidant activity independent of its actions on the TrkB receptor, protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity. Tropoflavin was also found to block methamphetamine-induced dopaminergic neurotoxicity.